Depression 10 Hz (120%) – FDA approved

Standard FDA approved protocol for depression performed over the left DLPFC for 36.5 minutes

Train 1
40 pulses at 10Hz

26.0s
Train 2
40 pulses at 10Hz

26.0s
Train 3
40 pulses at 10Hz

26.0s
Train 4
40 pulses at 10Hz

26.0s
Train 5
40 pulses at 10Hz

26.0s
Train 6
40 pulses at 10Hz

26.0s
Train 7
40 pulses at 10Hz

26.0s
Train 8
40 pulses at 10Hz

26.0s
Train 9
40 pulses at 10Hz

26.0s
Train 10
40 pulses at 10Hz

26.0s
Train 11
40 pulses at 10Hz

26.0s
Train 12
40 pulses at 10Hz

26.0s
Train 13
40 pulses at 10Hz

26.0s
Train 14
40 pulses at 10Hz

26.0s
Train 15
40 pulses at 10Hz

26.0s
Train 16
40 pulses at 10Hz

26.0s
Train 17
40 pulses at 10Hz

26.0s
Train 18
40 pulses at 10Hz

26.0s
Train 19
40 pulses at 10Hz

26.0s
Train 20
40 pulses at 10Hz

26.0s
Train 21
40 pulses at 10Hz

26.0s
Train 22
40 pulses at 10Hz

26.0s
Train 23
40 pulses at 10Hz

26.0s
Train 24
40 pulses at 10Hz

26.0s
Train 25
40 pulses at 10Hz

26.0s
Train 26
40 pulses at 10Hz

26.0s
Train 27
40 pulses at 10Hz

26.0s
Train 28
40 pulses at 10Hz

26.0s
Train 29
40 pulses at 10Hz

26.0s
Train 30
40 pulses at 10Hz

26.0s
Train 31
40 pulses at 10Hz

26.0s
Train 32
40 pulses at 10Hz

26.0s
Train 33
40 pulses at 10Hz

26.0s
Train 34
40 pulses at 10Hz

26.0s
Train 35
40 pulses at 10Hz

26.0s
Train 36
40 pulses at 10Hz

26.0s
Train 37
40 pulses at 10Hz

26.0s
Train 38
40 pulses at 10Hz

26.0s
Train 39
40 pulses at 10Hz

26.0s
Train 40
40 pulses at 10Hz

26.0s
Train 41
40 pulses at 10Hz

26.0s
Train 42
40 pulses at 10Hz

26.0s
Train 43
40 pulses at 10Hz

26.0s
Train 44
40 pulses at 10Hz

26.0s
Train 45
40 pulses at 10Hz

26.0s
Train 46
40 pulses at 10Hz

26.0s
Train 47
40 pulses at 10Hz

26.0s
Train 48
40 pulses at 10Hz

26.0s
Train 49
40 pulses at 10Hz

26.0s
Train 50
40 pulses at 10Hz

26.0s
Train 51
40 pulses at 10Hz

26.0s
Train 52
40 pulses at 10Hz

26.0s
Train 53
40 pulses at 10Hz

26.0s
Train 54
40 pulses at 10Hz

26.0s
Train 55
40 pulses at 10Hz

26.0s
Train 56
40 pulses at 10Hz

26.0s
Train 57
40 pulses at 10Hz

26.0s
Train 58
40 pulses at 10Hz

26.0s
Train 59
40 pulses at 10Hz

26.0s
Train 60
40 pulses at 10Hz

26.0s
Train 61
40 pulses at 10Hz

26.0s
Train 62
40 pulses at 10Hz

26.0s
Train 63
40 pulses at 10Hz

26.0s
Train 64
40 pulses at 10Hz

26.0s
Train 65
40 pulses at 10Hz

26.0s
Train 66
40 pulses at 10Hz

26.0s
Train 67
40 pulses at 10Hz

26.0s
Train 68
40 pulses at 10Hz

26.0s
Train 69
40 pulses at 10Hz

26.0s
Train 70
40 pulses at 10Hz

26.0s
Train 71
40 pulses at 10Hz

26.0s
Train 72
40 pulses at 10Hz

26.0s
Train 73
40 pulses at 10Hz

26.0s
Train 74
40 pulses at 10Hz

26.0s
Train 75
40 pulses at 10Hz

26.0s

This protocol is performed at 120% of motor threshold. The train(s) consist of 40 pulses: 10 pulses a second for a total of 4 seconds, followed by a break of 26.0 seconds. This is repeated 75 times. The total duration is 36 minutes 56 seconds, and the total number of pulses is 3000.

Parameters

Stimulation typeBiphasic
Stimulus amplitude (% of MT)120
Pulse frequency in train (Hz)10
Pulses in train40
Number of trains75
Intertrain interval(s)26.0
Total time00:36:56
Total pulses3000

Literature

O’Reardon, J.P., Solvason, H.B., Janicak, P.G., Sampson, S., Isenberg, K.E., Nahas, Z., McDonald, W.M., Avery, D., Fitzgerald, P.B., Loo, C., Demitrack, M.A., George, M.S., & Sackheim, H.A. Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized control trial. Biological Psychiatry, 62, 11, 1208-1216 (2007)

Videos

3:38 Locating DLPFC TMS

Finding DLPFC using the Beam Method

Dr. Rustin Berlow demonstrates the measurements needed to locate the Dorsolateral Prefrontal Cortex for the Beam Protocol.